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"Reduce 15 MG Slimming 500 Pills !! (50 Pack) 5 Boxes "
"Reduce 15 MG Slimming 500 Pills !! (50 Pack) 5 Boxes "
Price: $299.00
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Reduce 15 MG Slimming ++ Fastest Slimming & Top Hit Products.
You will receive 500 pills
(50 Pack) 5 Boxes
Composition
Each capsules of Reduce 15mg contains
Sibutramine 15mg
Product Description
SIBUTRAMINE belong to the category of appetite suppressant.
The Structural Formula:
1-(4-chlorophenyl)-N,N-dimethyl-a-(2-methylpropyl)-cyclobutanemethanamine
Molecular Formula:C17H26ClN
Molecular Weight:279.85 g/mol
Mechanism Of Action
Inhibits reuptake of norepinephrine, serotonin, and dopamine. May
stimulate satiety center in brain, causing appetite suppression.
Inhibits reuptake of Serotonin(5.H.T) nor adrenaline and to a lesser
extent, dopamine in Vivo and in vitro M1 and M2 Metabolite are
pharmacologically active and are up to about 100-fold more potent
reuptake inhibitors than sibutramine has no effects on dopamine
receptors, some thermogenic activity is evident at doses of 10mg
apparent low abuse potential in humans.Reduce (Sibutramine) produce its
therapeutic effect by Norepinephrine, Serotonin and dopamine reuptake
inhibition.
Pharmaco Kinetics
Reduce reaches maximum therapeutic concentration in 1.2hrs. Food
delays the absorption by 3hrs. Approximately 77% of the single oral dose
is absorbed. Steady state reached with in 4days. Reduce (Sibutramine)
is extensively bound and is rapidly and extensively distributed into
tissue. It undergoes extensive first pas metabolism and is primarily by
cytochromep4503A4 isoenzyme. Approximately 85% of the drug eliminated
through urine.
Indications
Management of obesity, including weight loss and maintenance of
weight loss and should be used in conjugation with a reduced calorie
diet. Contra Indications
Pregnancy and paediatric patients, hypersensitivity,patients
receiving MAO inhibitors,anorexia,nervosa, patients taking other
centrally acting appetite suppressant.
Adverse Effects
Dry mouth,anorexia, constipation,insomnia, dizziness.
Special Precautions
Monitor BP regularly when prescribing sibutramine.
Dosage
Its recommended for obese patients with an initial BMI 30kg/m2 or
27kg/m2 in the presence of the risk factors(e.g.
hypertension,diabetes,dyslipidemia).Initially 10mg of sibutramine is
given once daily with or without food. If there is inadequate weight
loss, the dose may be titrated after four weeks to a total of 15mg once
daily.
PAYMENT
I accept PAYPAL payments only. Your order will not be shipped until your payment has cleared.
SHIPPING
I only shipped to PAYPAL confirmed address. Items are despatch
within 1-2 days after payment has cleared. The shipping via Airmail
register post of Thailand Post. The package will arrive with in 7-25
days.
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Destination: Thailand |
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CUSTOM | parcel | $39.75 | $39.50 | | Destination: Worldwide |
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CUSTOM | economy air mail | $49.99 | $47.99 | | CUSTOM | Ems Air mail Shipping | $79.99 | $77.99 | |
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Type | Instructions to Buyer |
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Money Order | Please contract me at my mail: [email protected] |
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$0.00(Domestic) $0.00(International)
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