In order to save your item as an inventory profile, just check the "Save this item in my inventory" option as you are creating your listing.
Once the listing is created and saved, click on Inventory in Sales Manager (the link is under Display Options in the lefthand navigation bar.) Locate your item, and click on the item title. Then, select "Profile Item" at the top of the page, scroll to the bottom of the page and click the "Save" button. You will now see that your profile item will be highlighted in yellow on your inventory page.
After this is completed, you will see that the inventory profile has been added to the drop-down list on the Choose Category page under Apply Profile.
When you click to create brand new auctions, you will have the option to apply all of the details of that inventory profile item.